吴依璠

作者:发布时间:2020-03-16浏览次数:223

吴依璠

职称:讲师

邮箱:wuyifan@tiangong.edu.cn

专业:生物医学工程

研究方向

  1. 血管组织工程

  2. 血管干细胞生物学

学习经历

2014.09-2019.06 南开大学生物化学与分子生物学专业,理学博士

2017.10-2018.10 伦敦大学国王学院心血管系,联合培养博士

2010.09-2014.06 山东大学生物技术专业,理学学士

工作经历

2019.11-至今 澳门新浦京8455com从事教学和科研工作

代表性论文

[1] 吴依璠,智登科,Adam C. Midgley, 赵强,孔德领*,王恺* . 人工血管组织再生的细胞来源. 中国科学:生命科学,2019,49:1100.

[2] Shirin Issa Bhaloo#, Wu Yifan#, Alexandra Le Bras, Yu Baoqi, Gu Wenduo, Xie Yao, Deng Jiacheng, Wang Zhihong, Zhang Zhongyi, Kong Deling, Hu Yanhua, Qu Aijuan, Zhao Qiang*, Xu Qingbo*. Binding of Dickkopf-3 to CXCR7 Enhances Vascular Progenitor Cell Migration and Degradable Graft Regeneration. Circulation Research. 2018, 123(4): 451-466.

[3] Zhu Meifeng#, Wu Yifan#, Li Wen, Dong Xianhao, Chang Hong, Wang Kai, Wu Pingli, Zhang Jun, Fan Guanwei, Wang Lianyong, Liu Jianfeng, Wang Hongjun*, Kong Deling*. Biodegradable and elastomeric vascular grafts enable vascular remodeling. Biomaterials. 2018, 183: 306-318.

[4] Wu Yifan, Qin Yibo, Wang Zhihong*, Wang Jianing, Zhang Chuangnian, Li Chen, Kong Deling*. The regeneration of macro-porous electrospun poly(ε-caprolactone) vascular graft during long-term in situ implantation. Journal of Biomedical Materials Research Part B. 2017, 106(4), 1618-1627.

[5] Wang Zhihong#, Wu Yifan#, Wang Jianing, Zhang Chuangnian, Yan Hongyu, Zhu Meifeng, Wang Kai*, Li Chen, Xu Qingbo, Kong Deling*. The effect of resveratrol on modulation of endothelial cells and macrophages for rapid vascular regeneration from electrospunpoly(ε-caprolactone) scaffolds. ACS Applied Materials & Interfaces. 2017, 9(23):19541-19551.

[6] Wei Yongzhen#, Wu Yifan#, Zhao Runxia, Zhang Kaiyue, Adam C. Midgley, Kong Deling, Li Zongjin*, Zhao Qiang*. MSC-derived sEVs enhance patency and inhibit calcification of synthetic vascular grafts by immunomodulation in a rat model of hyperlipidemia. Biomaterials. 2019, 204: 13-24.

[7] Liu Jing#, Qin Yibo#, Wu Yifan, Sun Zhiting, Li Binhan, Jing Huimin, Zhang Chuangnian, Li Chen, Leng Xigang, Wang Zhihong*, Kong Deling*. Biomaterials Science. 2019. 7(3): 914-925.

[8] Qin Kang, Wu Yifan, Pan Yiwa, Wang Kai*, Kong Deling, Zhao Qiang*. Journal of Visualized Experiments. 2018, 136.

[9] Wang Juan#, Liu Lumei#, Wu Yifan, Manfred F Maitz, Wang Zhihong, Youngmi Koo, Ansha Zhao, Jagannathan Sankar, Kong Deling, Huang Nan*, Yeoheung Yun*. Acta biomaterialia. 2017, 50: 546-555.

[10] Wang Zhihong#, Zheng Wenting#, Wu Yifan, Wang Jianing, Zhang Xiuyuan, Wang Kai, Zhao Qiang, Kong Deling, Ke Tingyu, Li Chen. Biomaterials Science. 2016, 4: 1485-1492.

授权发明专利

2020.1.31可控释放白藜芦醇和/或白藜芦醇衍生物的载体及其制备方法与应用. ZL 2016 1 1033078.9,王志红,孔德领,吴依璠

代表性科研项目

  1. 参与国家自然科学基金重点项目,81530059,“生物活性小口径人工血管的构建及诱导血管再生机制研究”,2016/1-2020/1274万,在研。

  2. 参加国家自然科学基金面上项目,31771059,“巨噬细胞在人工血管组织再生中的作用机制研究“,2018.1-2022.160万,在研。